The role of miRNA regulation in response to hypoxia in gliomas

Glioblastoma multiforme (GBM) is the most aggressive and frequent adult brain tumour. Current therapy consists of debulking surgery followed by radiotherapy and temozolomide chemotherapy. The median survival is only 14 months post-therapy due to the high rates of recurrence. GBMs are known to be ver...

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Bibliographic Details
Main Author: Smith, Louise
Format: Thesis (University of Nottingham only)
Language:English
Published: 2023
Subjects:
Online Access:https://eprints.nottingham.ac.uk/72896/