A Reductive Amination Using Methyl Esters as Nominal Electrophiles
This report investigates a one-pot catalytic domino reaction for the synthesis of amines from methyl esters. The first step is a 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) catalysed amidation immediately followed by a zinc acetate catalysed reduction using phenyl silane as the terminal reductant. The...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
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| Online Access: | https://eprints.nottingham.ac.uk/71958/ |