Characterisation of GABAergic interneurons in a dual-hit neurodevelopmental model for schizophrenia

Schizophrenia is a debilitating mental illness distinguished by positive, negative, and cognitive symptoms. Pathogenesis begins in early neurodevelopment and leads to excitatory-inhibitory imbalance that is poorly managed by current treatments. Preclinical models used to understand the disease and e...

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Bibliographic Details
Main Author: Cale, Jennifer
Format: Thesis (University of Nottingham only)
Language:English
Published: 2023
Subjects:
Online Access:https://eprints.nottingham.ac.uk/71952/