Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes

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Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes

Hypertrophic cardiomyopathy (HCM) is the most common cardiomyopathy, estimated to affect 1:250 people, resulting in impaired cardiac function due to thickening of the left ventricle. Once disregarded as genomic junk, long non-coding ribonucleic acids (lncRNA) have emerged as key regulators of human...

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Bibliographic Details
Main Author:	Bodbin, S.E.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	iPSC-CM stem cell biology disease modelling CRISPR
Online Access:	https://eprints.nottingham.ac.uk/71672/

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