Linking molecular targets to hypertrophic cardiomyopathy using genome-edited human induced pluripotent stem cell cardiomyocytes
Hypertrophic cardiomyopathy (HCM) is the most common cardiomyopathy, estimated to affect 1:250 people, resulting in impaired cardiac function due to thickening of the left ventricle. Once disregarded as genomic junk, long non-coding ribonucleic acids (lncRNA) have emerged as key regulators of human...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2022
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| Online Access: | https://eprints.nottingham.ac.uk/71672/ |