The molecular basis of Gs protein efficacy at the b2- adrenoceptor

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The molecular basis of Gs protein efficacy at the b2- adrenoceptor

GPCRs are the largest family of transmembrane receptors in the human genome and currently represent 34% of all FDA approved medicines. The β2-adrenoceptor (β2AR) is a prototypical class A GPCR which is therapeutically relevant in asthma, whereby β2AR agonists relieve bronchoconstriction. Despite the...

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Bibliographic Details
Main Author:	Harwood, Clare
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	β2-adrenoceptor β2AR Gs protein efficacy
Online Access:	https://eprints.nottingham.ac.uk/71634/

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