The molecular basis of Gs protein efficacy at the b2- adrenoceptor
GPCRs are the largest family of transmembrane receptors in the human genome and currently represent 34% of all FDA approved medicines. The β2-adrenoceptor (β2AR) is a prototypical class A GPCR which is therapeutically relevant in asthma, whereby β2AR agonists relieve bronchoconstriction. Despite the...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2022
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| Online Access: | https://eprints.nottingham.ac.uk/71634/ |