Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias

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Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias

G protein coupled receptors (GPCRs) signal through a complex cellular network, with a range of temporally variable signalling responses generated by GPCR activation. Characterisation of GPCR ligands is generally taken from the ligand “affinity”, the ability to bind the receptor, and the ligand “effi...

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Bibliographic Details
Main Author:	Dijon, Nicola C
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	G protein coupled receptors GPCRs Novel complementation biosensors Signalling bias
Online Access:	https://eprints.nottingham.ac.uk/69368/

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