Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias
G protein coupled receptors (GPCRs) signal through a complex cellular network, with a range of temporally variable signalling responses generated by GPCR activation. Characterisation of GPCR ligands is generally taken from the ligand “affinity”, the ability to bind the receptor, and the ligand “effi...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2022
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| Online Access: | https://eprints.nottingham.ac.uk/69368/ |