A recombinant non-toxigenic Clostridioides difficile spore vaccine directed against toxigenic C. difficile

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A recombinant non-toxigenic Clostridioides difficile spore vaccine directed against toxigenic C. difficile

Clostridioides difficile (C. difficile) is the leading cause of hospital acquired diarrhoeal infection. Its pathology is mainly due to two toxins, TcdA and TcdB. The failure to treat recurrent infection can culminate in death and thus preventative measures are of urgent need. Current vaccine trials...

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Bibliographic Details
Main Author:	Aston, Carl
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	Clostridioides difficile Vaccine Non-toxigenic Toxigenic
Online Access:	https://eprints.nottingham.ac.uk/69093/

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