A recombinant non-toxigenic Clostridioides difficile spore vaccine directed against toxigenic C. difficile
Clostridioides difficile (C. difficile) is the leading cause of hospital acquired diarrhoeal infection. Its pathology is mainly due to two toxins, TcdA and TcdB. The failure to treat recurrent infection can culminate in death and thus preventative measures are of urgent need. Current vaccine trials...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2022
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| Online Access: | https://eprints.nottingham.ac.uk/69093/ |