Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
Colorectal cancer (CRC) is one of the most prevalent cancers in the world, especially in western countries. It is a multifactorial malignant disease that involves multiple genetic mutations and epigenetic alterations. A large number of patients present with metastasis at the first diagnosis and the...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/68970/ |