Investigating a human DNA repair helicase that supports CRISPR editing

In the last decade, CRISPR-associated proteins such as Cas9 and Cas12a have become powerful gene-editing tools for research, with great potential for therapeutic applications. However, barriers remain to their successful implementation, one of which is understanding the interaction of these systems...

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Bibliographic Details
Main Author: Cubbon, Andrew
Format: Thesis (University of Nottingham only)
Language:English
Published: 2022
Subjects:
Online Access:https://eprints.nottingham.ac.uk/68641/