Can bioluminescence resonance energy transfer be used to elucidate structural and binding information about the ABCG2 transporter?

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Can bioluminescence resonance energy transfer be used to elucidate structural and binding information about the ABCG2 transporter?

ATP binding cassette G2 (ABCG2) is a multidrug transporter involved in cancer cell resistance to chemotherapeutics. Uncovering ABCG2 structural and binding information and screening for potential inhibitors is crucial for increasing chemotherapy effectiveness and improving cancer prognoses. The pres...

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Bibliographic Details
Main Author:	Morris, Joseph
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	ATP binding cassette G2 ABCG2 Bioluminescence resonance energy transfer BRET
Online Access:	https://eprints.nottingham.ac.uk/68414/

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