Can bioluminescence resonance energy transfer be used to elucidate structural and binding information about the ABCG2 transporter?
ATP binding cassette G2 (ABCG2) is a multidrug transporter involved in cancer cell resistance to chemotherapeutics. Uncovering ABCG2 structural and binding information and screening for potential inhibitors is crucial for increasing chemotherapy effectiveness and improving cancer prognoses. The pres...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2022
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| Online Access: | https://eprints.nottingham.ac.uk/68414/ |