Preparation of potent and selective αvβ6 integrin inhibitors for the treatment of idiopathic pulmonary fibrosis and synthetic approaches towards the total synthesis of mescengricin

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Preparation of potent and selective αvβ6 integrin inhibitors for the treatment of idiopathic pulmonary fibrosis and synthetic approaches towards the total synthesis of mescengricin

Idiopathic pulmonary fibrosis (IPF) is a terminal illness characterised by excessive build-up of scar tissue within the lungs. Despite a relatively high incidence amongst the population, there are no currently available treatments that prolong the estimated lifespan of an affected individual beyond...

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Bibliographic Details
Main Author:	Robinson, Henry Duncan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Integrins; Inhibitors; Pulmonary fibrosis; Idiopathic pulmonary fibrosis; Integrin inhibitors
Online Access:	https://eprints.nottingham.ac.uk/66919/

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