Preparation of potent and selective αvβ6 integrin inhibitors for the treatment of idiopathic pulmonary fibrosis and synthetic approaches towards the total synthesis of mescengricin
Idiopathic pulmonary fibrosis (IPF) is a terminal illness characterised by excessive build-up of scar tissue within the lungs. Despite a relatively high incidence amongst the population, there are no currently available treatments that prolong the estimated lifespan of an affected individual beyond...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2021
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| Online Access: | https://eprints.nottingham.ac.uk/66919/ |