Tying the CNOT: CNOT1 regulates poly(A) tail length at the end and the beginning
Poly(A) tails affect multiple aspects of gene regulation: they help identify mRNAs for nuclear export, enhance translation efficiency, and are essential to regulating mRNA degradation rate. A poly(A) tail of 200-250 residues is thought to be uniformly added to newly synthesised mRNA and later gradua...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
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| Online Access: | https://eprints.nottingham.ac.uk/66534/ |