Discovery of highly potent and selective phosphatidylinositol 3-kinase-δ inhibitors for the treatment of blood cancers and autoimmune diseases

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Discovery of highly potent and selective phosphatidylinositol 3-kinase-δ inhibitors for the treatment of blood cancers and autoimmune diseases

Phosphatidylinositol-3-kinase (PI3K) are a group of the lipid kinases superfamily, that play a crucial role in signalling pathways involved in the regulation of numerous cellular processes such as survival, growth, proliferation and differentiation. PI3K δ belongs to the class-IA subset of PI3Ks and...

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Bibliographic Details
Main Author:	Buzrieda, Anas
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Phosphatidylinositol 3-kinase-δ inhibitors Blood cancers Autoimmune diseases
Online Access:	https://eprints.nottingham.ac.uk/66124/

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