Discovery of highly potent and selective phosphatidylinositol 3-kinase-δ inhibitors for the treatment of blood cancers and autoimmune diseases
Phosphatidylinositol-3-kinase (PI3K) are a group of the lipid kinases superfamily, that play a crucial role in signalling pathways involved in the regulation of numerous cellular processes such as survival, growth, proliferation and differentiation. PI3K δ belongs to the class-IA subset of PI3Ks and...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2021
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| Online Access: | https://eprints.nottingham.ac.uk/66124/ |