Anticancer effects of combined gamma-tocotrienol and 13-cis retinoic acid against neuroblastoma cells and xenografts

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Anticancer effects of combined gamma-tocotrienol and 13-cis retinoic acid against neuroblastoma cells and xenografts

High-risk neuroblastoma mainly affects young children and is known to be resistant to treatment (surgery and chemotherapy) which is often attributed to amplified MYCN. Overexpressed Bcl-2 protein is also frequently a feature of neuroblastoma tumours. 13-cis retinoic acid (13cRA) is used as a differe...

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Bibliographic Details
Main Author:	Ch'ng, Qin Ting
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	protein; neuroblastoma; Bcl-2; tocotrienol; retinoic acid; cell lines; xenografts
Online Access:	https://eprints.nottingham.ac.uk/65806/

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