Anticancer effects of combined gamma-tocotrienol and 13-cis retinoic acid against neuroblastoma cells and xenografts
High-risk neuroblastoma mainly affects young children and is known to be resistant to treatment (surgery and chemotherapy) which is often attributed to amplified MYCN. Overexpressed Bcl-2 protein is also frequently a feature of neuroblastoma tumours. 13-cis retinoic acid (13cRA) is used as a differe...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
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| Online Access: | https://eprints.nottingham.ac.uk/65806/ |