Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts

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Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts

Currently, in vivo mouse models are the gold standard for testing cancer treatments before progression to human trials, often using tissue derived directly from patient tumours (patient-derived xenografts, PDXs) propagated in mice to generate sufficient cells for an experiment. A 3D in vitro system...

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Bibliographic Details
Main Author:	Jones, Sal
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	3D cancer model breast cancer patient-derived xenografts
Online Access:	https://eprints.nottingham.ac.uk/65724/

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