Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts
Currently, in vivo mouse models are the gold standard for testing cancer treatments before progression to human trials, often using tissue derived directly from patient tumours (patient-derived xenografts, PDXs) propagated in mice to generate sufficient cells for an experiment. A 3D in vitro system...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/65724/ |