Engineering ‘extracellular matrix factories’ to study how the extracellular microenvironment regulates gene expression

The extracellular matrix (ECM) is a specialised scaffold as well as a biochemical signalling platform for cells. The ECM plays a key role in gene regulation, with components such as tenascin-C (TN-C) being implicated in post-transcriptional regulation of inflammatory genes. However, the lack of phys...

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Bibliographic Details
Main Author: Tomlin, Hannah
Format: Thesis (University of Nottingham only)
Language:English
Published: 2021
Subjects:
Online Access:https://eprints.nottingham.ac.uk/65577/