An investigation into the function and mechanism of a GRK5-L41 polymorphism using human pluripotent cell-derived cardiomyocytes
A single-nucleotide polymorphism (SNP) in G protein-coupled receptor kinase 5 (termed GRK5-Q41L) was reported to be associated with a low mortality rate for patients with heart failure and cardiac ischemia (Liggett et al., 2008). An in vitro study on transfected cells and transgenic mice suggested t...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/65137/ |