Synthesis of an isomer of lycoplanine a via cascade cyclization to construct the spiro-N,O-acetal moiety
An isomer of lycoplanine A with a 6/10/5/5 tetracyclic skeleton was synthesized using D–A reaction and cascasde reaction to respectively construct the [9.2.2] pentadecane skeleton and the challenging 1-oxa-6-azaspiro[4.4]nonane spirocenter. Morever, detailed DFT calculations were conducted to explai...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2021
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| Online Access: | https://eprints.nottingham.ac.uk/64854/ |