Investigating the impact of the surface on the physical stability of drug: polymer amorphous solid dispersions
The formulation of drugs in the amorphous state offers potential advantages, including enhanced apparent solubility and hence bioavailability, although this comes at the cost of instability for recrystallisation. Recently, the importance of surface-enhanced crystallisation (SEC) mechanism on five am...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/64089/ |