Targeting the hypoxic expression of epidermal growth factor receptor
Investigating translation regulation of epidermal growth factor receptor (EGFR) is a growing concern in the context of advanced breast cancer. The 5’ untranslated region (UTR) of EGFR mRNA contains an internal ribosome entry site (IRES) that permits hypoxic expression. This allows targeting of the e...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
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| Online Access: | https://eprints.nottingham.ac.uk/64001/ |