RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions

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RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated (Cas) proteins build adaptive immunity against mobile genetic elements (MGEs) in prokaryotes. The memory of previously encountered MGEs is established by DNA capture and integration into CRISPR loci catalysed by...

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Bibliographic Details
Main Author:	Lau, Chun H.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Clustered regularly interspaced short palindromic repeats CRISPR Mobile genetic elements MGEs Casposases Casposase-Cas9 fusions
Online Access:	https://eprints.nottingham.ac.uk/63620/

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