RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated (Cas) proteins build adaptive immunity against mobile genetic elements (MGEs) in prokaryotes. The memory of previously encountered MGEs is established by DNA capture and integration into CRISPR loci catalysed by...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/63620/ |