Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma

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Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma

Asthma is a chronic inflammatory disease of the airways, affecting 5.4 million people in the UK. Asthma pathology is characterised by airway hyper-responsiveness, bronchoconstriction, and airway remodelling. Airway remodelling is particularly prominent in severe asthma and describes structural chang...

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Bibliographic Details
Main Author:	Middlewick, Robert James
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	GPCR G-protein Transforming growth factor beta Airway smooth muscle Asthma
Online Access:	https://eprints.nottingham.ac.uk/63595/

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