Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma

Asthma is a chronic inflammatory disease of the airways, affecting 5.4 million people in the UK. Asthma pathology is characterised by airway hyper-responsiveness, bronchoconstriction, and airway remodelling. Airway remodelling is particularly prominent in severe asthma and describes structural chang...

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Bibliographic Details
Main Author: Middlewick, Robert James
Format: Thesis (University of Nottingham only)
Language:English
Published: 2020
Subjects:
Online Access:https://eprints.nottingham.ac.uk/63595/