Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides

Ruthenium polypyridyl complexes which can sensitise the photo-oxidation of nucleic acids and other biological molecules show potential for photo-therapeutic applications. In this article a combination of transient visible absorption (TrA) and time-resolved infra-red (TRIR) spectroscopy are used to c...

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Bibliographic Details
Main Authors: Keane, Páraic M., O'Sullivan, Kyra, Poynton, Fergus E., Poulsen, Bjørn C., Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Sun, Xue-Zhong, George, Michael W., Gunnlaugsson, Thorfinnur, Quinn, Susan J., Kelly, John M.
Format: Article
Language:English
Published: Royal Society of Chemistry 2020
Online Access:https://eprints.nottingham.ac.uk/63449/