Effect of cigarette smoke extract and hypoxia on vasoactive gene expression and mediator release in human pulmonary artery smooth muscle and endothelial cells

Background: Pulmonary hypertension is a common and serious complication of COPD. Studies suggest that hypoxia and cigarette smoke (CS) can cause vascular remodelling in COPD as a result of cell proliferation; however, the underlying cause is not fully understood. In addition, it is suggested that th...

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Bibliographic Details
Main Author: Alqarni, Abdullah Abdulghani M.
Format: Thesis (University of Nottingham only)
Language:English
English
Published: 2020
Subjects:
Online Access:https://eprints.nottingham.ac.uk/61505/