Elucidating the molecular mechanism of drug binding and translocation by the multidrug transporter ABCG2

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Elucidating the molecular mechanism of drug binding and translocation by the multidrug transporter ABCG2

Many drug resistant tumours express one or more of the three main drug efflux transporters, P-glycoprotein (ABCB1), multidrug resistance protein 1 (MRP1; ABCC1) and breast cancer resistance protein (ABCG2). These transporters facilitate the export of diverse range of structurally unrelated compounds...

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Bibliographic Details
Main Author:	Kapoor, Parth
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	ABC transporter Multidrug resistance ABCG2
Online Access:	https://eprints.nottingham.ac.uk/61418/

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