eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival

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eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival

Colorectal cancer is the third most common cancer, leading to 700,000 deaths a year worldwide. Regions of hypoxia (<1% O2) are present in around 50% of colorectal tumours. Hypoxia is associated with resistance to chemotherapy, radiotherapy and worse patient outcome. The process of protein synthes...

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Bibliographic Details
Main Author:	Bolland, Hannah
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Colorectal cancer; Hypoxia; Hypoxic regulation; Cancer cells
Online Access:	https://eprints.nottingham.ac.uk/60968/

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