eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival
Colorectal cancer is the third most common cancer, leading to 700,000 deaths a year worldwide. Regions of hypoxia (<1% O2) are present in around 50% of colorectal tumours. Hypoxia is associated with resistance to chemotherapy, radiotherapy and worse patient outcome. The process of protein synthes...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/60968/ |