New chemistry to support the search for more effective opioids
Herein is presented a synthesis route to obtain noroxymorphone, a vital intermediate in the manufacture of opioid medicines, using the major ingredient in opium – morphine as the starting material. Two steps of Albright-Goldman oxidation and the formation of diene are combined in one pot to enhance...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/60621/ |