Advances in the application of N-sulfinyl auxiliaries to the synthesis of pyrrolidines and α-amino acid derivatives
Pyrrolidines are widely prevalent in pharmaceuticals, catalysis and agrochemicals. The (3+2) cycloaddition of azomethine ylides with alkenes is one of the most powerful methods for pyrrolidine synthesis. This reaction creates 2 σ-bonds and up to 4 new stereocentres in one reaction. Methods for the s...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/60592/ |