Investigating genotype and sex susceptibility to a systemic infection in APPswe/PS1ΔE9 mouse model of Alzheimer’s disease, at an early stage of amyloid plaque deposition

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Investigating genotype and sex susceptibility to a systemic infection in APPswe/PS1ΔE9 mouse model of Alzheimer’s disease, at an early stage of amyloid plaque deposition

Systemic bacterial infection can worsen Alzheimer’s disease (AD) progression by compromising the central microglia and astrocytes immune response implicated in the clearance of amyloid-β (Aβ) plaques, one of the AD hallmarks. In the present thesis, I investigated whether systemic infection with lipo...

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Bibliographic Details
Main Author:	Agostini, Alessandra
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Sex susceptibility Systemic infection Alzheimer’s disease
Online Access:	https://eprints.nottingham.ac.uk/60555/

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