Investigating genotype and sex susceptibility to a systemic infection in APPswe/PS1ΔE9 mouse model of Alzheimer’s disease, at an early stage of amyloid plaque deposition
Systemic bacterial infection can worsen Alzheimer’s disease (AD) progression by compromising the central microglia and astrocytes immune response implicated in the clearance of amyloid-β (Aβ) plaques, one of the AD hallmarks. In the present thesis, I investigated whether systemic infection with lipo...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/60555/ |