Human pluripotent stem cells derived-cardiomyocytes (hPSC-CMs) to assess the impact of drug- and gene-induced changes on cell function
The majority of data available for drug predictive safety and disease/polymorphism modelling are based on results from genetic association studies or from models other than humans, which can lead to conflicting mechanistic explanations. This thesis considers whether human pluripotent stem cell-deriv...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/60206/ |