An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes

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An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes

The M1 muscarinic acetylcholine receptor (mAChR) is a G protein-coupled receptor (GPCR), linked to cellular signalling pathways via increased intracellular calcium concentrations. The M1 mAChR has been implemented in a number of physiological and pathological signalling mechanisms in the central ne...

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Bibliographic Details
Main Author:	Carpenter, Jessica
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Muscarinic receptors; G proteins; Allosteric regulation; Astrocytes;
Online Access:	https://eprints.nottingham.ac.uk/60163/

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