Synthesis, detection, and quantification of modified nucleotides in RNA

Background: N6-methyladenosine (m6A) is the most abundant internal modification of mRNA. m6A regulates almost every stage in the mRNA life cycle with essential roles in splicing, polyadenylation, nuclear export, stability, translation, and degradation. m6A is essential for normal development of euka...

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Bibliographic Details
Main Author: Baron, Francis
Format: Thesis (University of Nottingham only)
Language:English
Published: 2020
Subjects:
Online Access:https://eprints.nottingham.ac.uk/60070/