Genetic and biochemical analysis of the Hel308 Helicase in the Archaeon Haloferax volcanii

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Genetic and biochemical analysis of the Hel308 Helicase in the Archaeon Haloferax volcanii

Hel308 is a monomeric 3’ to 5’ DNA helicase conserved throughout archaea and metazoans, but is absent from bacteria and fungi. Hel308 acts analogously to RecQ-family helicases, which serve as guardians of genome stability. Hel308 has been implicated in a variety of overlapping DNA repair pathways, i...

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Bibliographic Details
Main Author:	Lever, Rebecca
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	DNA helicase; Haloferax volcanii; Helicase activity; DNA replication; DNA repair
Online Access:	https://eprints.nottingham.ac.uk/60024/

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