Macrocyclic peptides as inhibitors of protein-protein interactions
Inhibition of the Keap1-Nrf2 protein-protein interaction (PPI) is thought to have therapeutic potential in several diseases including neurodegenerative conditions such as Alzheimer’s and Parkinson’s, as well as cardiovascular diseases and cancer. Cyclic peptides provide interesting scaffolds that no...
| Main Author: | Smith, Frances |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English English |
| Published: |
2020
|
| Online Access: | https://eprints.nottingham.ac.uk/59958/ |
Similar Items
A cyclic peptide inhibitor of the iNOS–SPSB protein–protein interaction as a potential anti-infective agent
by: Mohd Shariff, Fairolniza, et al.
Published: (2018)
by: Mohd Shariff, Fairolniza, et al.
Published: (2018)
Small molecule inhibitors of the p53-MDM2 protein-protein interaction
by: Fitzgerald, Ross Patrick
Published: (2011)
by: Fitzgerald, Ross Patrick
Published: (2011)
Design, synthesis, and optimisation of highly selective macrocyclic CDK9 inhibitors
by: Gao, Rui
Published: (2018)
by: Gao, Rui
Published: (2018)
Macrocyclic gelators
by: Goh, Ching, et al.
Published: (2013)
by: Goh, Ching, et al.
Published: (2013)
Nano-encapsulation of proteins and peptides
by: Ibrahim Ali, Noorbatcha, et al.
Published: (2017)
by: Ibrahim Ali, Noorbatcha, et al.
Published: (2017)
Protein and peptide biopharmaceuticals: An overview
by: Agyei, D., et al.
Published: (2017)
by: Agyei, D., et al.
Published: (2017)
Structure-based design of peptide inhibitors for Protein Arginine Deiminase Type IV (PAD4)
by: Teo, Chian Ying, et al.
Published: (2018)
by: Teo, Chian Ying, et al.
Published: (2018)
Novel furan-containing peptide-based inhibitors of protein arginine deiminase type IV (PAD4)
by: Teo, Chian Ying, et al.
Published: (2017)
by: Teo, Chian Ying, et al.
Published: (2017)
Vesicles for transdermal delivery of peptides and proteins
by: Benson, Heather
Published: (2016)
by: Benson, Heather
Published: (2016)
Utilization and prospect of purification technologies in natural proteins, peptides and recombinant proteins
by: Eskandari, Azadeh, et al.
Published: (2024)
by: Eskandari, Azadeh, et al.
Published: (2024)
Studies on functionalised macrocyclic ligands
by: Tei, Lorenzo
Published: (2001)
by: Tei, Lorenzo
Published: (2001)
Antioxidative peptides derived from food proteins
by: Agyei, D., et al.
Published: (2015)
by: Agyei, D., et al.
Published: (2015)
Proteins and peptides: Strategies for delivery to and across the skin
by: Benson, Heather, et al.
Published: (2008)
by: Benson, Heather, et al.
Published: (2008)
Antifreeze peptides derived from fungal protein
by: Abdul Rahman, Mohd Basyaruddin, et al.
Published: (2009)
by: Abdul Rahman, Mohd Basyaruddin, et al.
Published: (2009)
Free Energy Calculations of the Interactions of c-Jun-based Synthetic Peptides with the c-Fos Protein
by: Zuo, Zhili, et al.
Published: (2012)
by: Zuo, Zhili, et al.
Published: (2012)
Optimization of protein-protein docking for predicting Fc-protein interactions
by: Agostino, Mark, et al.
Published: (2016)
by: Agostino, Mark, et al.
Published: (2016)
Formulation of chitosan-based nanoparticles for delivery of proteins and peptides
by: Vellore Janarthanan, Mohanraj
Published: (2003)
by: Vellore Janarthanan, Mohanraj
Published: (2003)
Streptococcus pyogenes proteins involved in resistance to
antimicrobial peptides
by: Shahdan, Intan Azura, et al.
Published: (2010)
by: Shahdan, Intan Azura, et al.
Published: (2010)
Antioxidative peptides from food proteins : a review.
by: Sarmadi, Bahareh H., et al.
Published: (2010)
by: Sarmadi, Bahareh H., et al.
Published: (2010)
Characterisation of essential proteins in proteins interaction networks
by: Sakhinah Abu Bakar,, et al.
Published: (2013)
by: Sakhinah Abu Bakar,, et al.
Published: (2013)
Discovery of new inhibitor for the protein arginine deiminase type 4 (PAD4) by rational design of α-enolase-derived peptides
by: Ahmad Nadzirin, Izzuddin, et al.
Published: (2021)
by: Ahmad Nadzirin, Izzuddin, et al.
Published: (2021)
Investigation of protein arginine methyltransferase
bisubstrate inhibitors
by: Al-noori, Alaa
Published: (2020)
by: Al-noori, Alaa
Published: (2020)
Design and synthesis of protein arginine methyltransferase inhibitors
by: Hong, Wei
Published: (2010)
by: Hong, Wei
Published: (2010)
The Use of Peptide-Membrane Interactions in the Design of Selective and Potent Sodium Channel Inhibitors
by: Schroeder, C., et al.
Published: (2018)
by: Schroeder, C., et al.
Published: (2018)
Peptide inhibitors of xenoreactive antibodies mimic the interaction profile of the native carbohydrate antigens
by: Agostino, Mark, et al.
Published: (2011)
by: Agostino, Mark, et al.
Published: (2011)
The development of Rab27-effector protein interaction inhibitors for treatment of cancer cell invasion and proliferation
by: Al-Saad, Raghdan Zeki Chillab
Published: (2017)
by: Al-Saad, Raghdan Zeki Chillab
Published: (2017)
Protein-protein interactions during Japanese encephalitis infection
by: Magdline Sia, Henry Sum.
Published: (2007)
by: Magdline Sia, Henry Sum.
Published: (2007)
High-pressure studies of macrocycle coordination complexes
by: Tidey, Jeremiah P.
Published: (2016)
by: Tidey, Jeremiah P.
Published: (2016)
Macrocyclic alkanes: A new class of biomarker
by: Audino, Michiele, et al.
Published: (2001)
by: Audino, Michiele, et al.
Published: (2001)
Anti-diabetic action of Lupinus angustifolius seed proteins and peptides
by: Tapadia, Mrunmai
Published: (2019)
by: Tapadia, Mrunmai
Published: (2019)
Food-derived multifunctional bioactive proteins and peptides: Sources and production
by: Agyei, D., et al.
Published: (2015)
by: Agyei, D., et al.
Published: (2015)
Noncovalent Interactions in SIESTA Using the vdW-DF Functional: S22 Benchmark and Macrocyclic Structures
by: Carter, Damien, et al.
Published: (2012)
by: Carter, Damien, et al.
Published: (2012)
Studies on the binding and interaction of neolactotetraosylceramide and peptides with dengue virus type 2 envelope protein / Asfarina Amir Hassan
by: Asfarina, Amir Hassan
Published: (2019)
by: Asfarina, Amir Hassan
Published: (2019)
Secreted frizzled-related protein 4: An angiogenesis inhibitor
by: Muley, A., et al.
Published: (2010)
by: Muley, A., et al.
Published: (2010)
Peptide inhibitors against influenza virus
by: Mohamed Ibrhaim, Mohamed Rajik, et al.
Published: (2011)
by: Mohamed Ibrhaim, Mohamed Rajik, et al.
Published: (2011)
Peptide inhibitors of Macrobrachium rosenbergii nodavirus
by: Thong, Qiu Xian, et al.
Published: (2018)
by: Thong, Qiu Xian, et al.
Published: (2018)
Carbene footprinting accurately maps binding sites in protein–ligand and protein–protein interactions
by: Manzi, Lucio, et al.
Published: (2016)
by: Manzi, Lucio, et al.
Published: (2016)
Inhibiting protein–protein interactions in telomeres as an approach to cancer chemotherapy
by: Salih, Twana
Published: (2016)
by: Salih, Twana
Published: (2016)
The development of machine learning based software for predicting protein-protein interactions and protein function from protein primary structure
by: Othman, Muhamad Razib, et al.
Published: (2007)
by: Othman, Muhamad Razib, et al.
Published: (2007)
The Structure of Glycosaminoglycans and their Interactions with Proteins
by: Gandhi, Neha, et al.
Published: (2008)
by: Gandhi, Neha, et al.
Published: (2008)
Similar Items
-
A cyclic peptide inhibitor of the iNOS–SPSB protein–protein interaction as a potential anti-infective agent
by: Mohd Shariff, Fairolniza, et al.
Published: (2018) -
Small molecule inhibitors of the p53-MDM2 protein-protein interaction
by: Fitzgerald, Ross Patrick
Published: (2011) -
Design, synthesis, and optimisation of highly selective macrocyclic CDK9 inhibitors
by: Gao, Rui
Published: (2018) -
Macrocyclic gelators
by: Goh, Ching, et al.
Published: (2013) -
Nano-encapsulation of proteins and peptides
by: Ibrahim Ali, Noorbatcha, et al.
Published: (2017)