Macrocyclic peptides as inhibitors of protein-protein interactions

Inhibition of the Keap1-Nrf2 protein-protein interaction (PPI) is thought to have therapeutic potential in several diseases including neurodegenerative conditions such as Alzheimer’s and Parkinson’s, as well as cardiovascular diseases and cancer. Cyclic peptides provide interesting scaffolds that no...

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Bibliographic Details
Main Author: Smith, Frances
Format: Thesis (University of Nottingham only)
Language:English
English
Published: 2020
Online Access:https://eprints.nottingham.ac.uk/59958/