Development of three-dimensional spheroid models for the analysis of medulloblastoma drug response and metastatic dissemination
Introduction: Medulloblastoma, the most common malignant paediatric brain tumour, is a heterogeneous disease with tumours classified based on their histological and molecular profiles. Studying medulloblastoma in vitro is challenging, as traditional two-dimensional (2D) cell culture models fail to r...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/59904/ |