Using high-throughput approaches to unveil sporulation and germination mechanisms in Clostridium sporogenes

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Using high-throughput approaches to unveil sporulation and germination mechanisms in Clostridium sporogenes

Intravenously injected clostridial spores infiltrate and selectively germinate in the hypoxic regions of solid tumours. The exquisite selectivity of this natural phenomenon is being exploited to bring about tumour destruction by engineering the delivered clostridia to enzymatically convert a subsequ...

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Bibliographic Details
Main Author:	Mesquita Rodrigues, Raquel
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Clostridium sporogenes; Genes; Bacteria; Prodrugs
Online Access:	https://eprints.nottingham.ac.uk/59874/

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